Testimonials
“The mesoSPIM microscope is a tremendous device, … much less expensive, more flexible and gives more robust higher quality images than any of the commercial systems currently available.”
“It is very stable, easy to use and robust. Mostly used with CUBIC or DBE cleared material. This stability is mostly due to the fixed relationships between all the components and the polished stable nature of the software.”
“Almost all our data is stitched multipanel (we use Imaris Stitcher) and it really does provide completely flat perfectly stitched data sets. We are very happy with the device.”
“I used building this as a bit of a training exercise for my staff who remain a bit mystified about the core principles of basic optical design. The guides on github and the pictures were super useful.”
“You don’t really need to understand optics to make this device work, as long as you follow the instructions carefully your build should be successful… Though it does help to understand collimation etc but your instructions are solid so a less experienced builder should be able to get things running.”
“You have done a great job of building a solid software platform that makes integrating the system with flexibility really easy. The only file that needs to be tweaked is the primary config file and once that is set up very few changes need to be made to it.”
— Simon C. Watkins, Ph.D., FRCPath, Distinguished Professor and Vice Chair Cell Biology, Professor Immunology, Director Center for Biologic Imaging, University of Pittsburgh. (August 2024)
“We needed a solution for rapid screening of numerous samples to optimize tissue clearing workflows. The Benchtop mesoSPIM was chosen due to its accessibility, ease of operation, and reliability.”
“The build process was straightforward. The most tedious aspect was configuring the software, but even that was manageable. … It took us just a few hours to build, in part because we opted for a single-sided illumination variant and reused parts from the original mesoSPIM for the illumination train.”
“We’re happy with the results. They are as expected.”
— Kevin Dean, Ph.D., Assistant Professor, Microscopy Innovation Lab, University of Texas Southwestern Medical Center. (August 2024)