#1 - Helmchen Lab, Brain Research Institute, University of Zurich, Switzerland
The oldest mesoSPIM saw first light in October 2015 (as a Version 0). The most recent upgrade in May 2018 brought it up to Version 4. The microscope is accessible within collaborations with the Helmchen lab.
#3 - Advanced Lightsheet Imaging Center, Wyss Center, Geneva, Switzerland
The first mesoSPIM outside of Zurich saw first light as a Version 4 in March 2018. It is open to users from both academia and industry. The facility also contains a CLARITY-optimized light-sheet microscope (COLM) for high-resolution imaging.
#5 - Advanced Microscopy Facility, Sainsbury Wellcome Centre for Neural Circuits and Behaviour, London, UK
The fifth mesoSPIM (and the first outside of Switzerland) became operational in December 2018.
#6 - Aguzzi Lab, Institute of Neuropathology, University Hospital Zurich, Switzerland
The first mesoSPIM V5 was set up in early August 2019. Together with mesoSPIM #2, it forms a high-throughput imaging platform.
#9 - Ertürk lab at the Institute for Tissue Engineering and Regenerative Medicine, Helmholtz Center Munich, Germany
The instrument was built by Tzu-Lun Wang, Mihail Todorov and Fabian F. Voigt and took its first images on November 8th, 2019.
#15 - Cardiac Imaging Laboratory at European Laboratory of Nonlinear Spectroscopy (LENS), Sesto Fiorentino, Italy
The first mesoSPIM in Italy was set up by Leonardo Sacconi in the summer of 2021. The microscope is used for reconstructing cleared whole mouse hearts. The detection arm uses large-sensor back-illuminated sCMOS camera with a high-resolution 2X telecentric lens.