#1 - Helmchen Lab, Brain Research Institute, University of Zurich, Switzerland
The oldest mesoSPIM saw first light in October 2015 (as a Version 0). The most recent upgrade in May 2018 brought it up to Version 4. The microscope is accessible within collaborations with the Helmchen lab.
#2 - Aguzzi Lab, Institute of Neuropathology, University Hospital Zurich, Switzerland
The second oldest mesoSPIM was set up as a Version 3 in July 2017 and upgraded to V4 in May 2018.
#3 - Advanced Lightsheet Imaging Center, Wyss Center, Geneva, Switzerland
The first mesoSPIM outside of Zurich saw first light as a Version 4 in March 2018. It is open to users from both academia and industry. The facility also contains a CLARITY-optimized light-sheet microscope (COLM) for high-resolution imaging.
#4 - The Center for Microscopy and Image Analysis, University of Zurich, Switzerland
mesoSPIM #4 was set up in May 2018. It is open to users of the Center for Microscopy and Image Analysis.
#5 - Advanced Microscopy Facility, Sainsbury Wellcome Centre for Neural Circuits and Behaviour, London, UK
The fifth mesoSPIM (and the first outside of Switzerland) became operational in December 2018.
#6 - Aguzzi Lab, Institute of Neuropathology, University Hospital Zurich, Switzerland
The first mesoSPIM V5 was set up in early August 2019. Together with mesoSPIM #2, it forms a high-throughput imaging platform.
#7 - Systems Biology Imaging Platform, Max Delbrück Center for Molecular Medicine, Berlin, Germany
The instrument was built by Andrew Woehler and took its first images in late August 2019.
#8 - Fu Yu’s lab at Singapore Bioimaging Consortium, A*STAR, Singapore
The instrument was built by Menghan Wang and took its first images in September 2019.
#9 - Ertürk lab at the Institute for Tissue Engineering and Regenerative Medicine, Helmholtz Center Munich, Germany
The instrument was built by Tzu-Lun Wang, Mihail Todorov and Fabian F. Voigt and took its first images on November 8th, 2019.
#10 - Busche lab at the UK Dementia Research Institute, University College London, UK
The instrument was set up by Bruno Pichler and his team at Independent Neuroscience Services in late December, 2019.
#11 - Oertner lab at the Institute for Synaptic Physiology - Center for Molecular Neurobiology Hamburg (ZMNH), Germany.
The instrument became operational in Summer 2020.
#12 - Microscopy Innovation Lab, University of Texas Southwestern, Dallas, USA
The first mesoSPIM in the United States was set up by Saumya Vora and Kevin Dean in Summer 2020.
#13 - Allen Institute for Brain Science, Seattle, USA
The first mesoSPIM on the West Coast was set up by Rusty Nicovich in 2020.
#14 - Prospective Instruments, Dornbirn, Austria
This mesoSPIM became operational in Summer 2021 and is accessible via the Prospective Instruments Imaging Service.
#15 - Cardiac Imaging Laboratory at European Laboratory of Nonlinear Spectroscopy (LENS), Sesto Fiorentino, Italy
The first mesoSPIM in Italy was set up by Leonardo Sacconi in the summer of 2021. The microscope is used for reconstructing cleared whole mouse hearts. The detection arm uses large-sensor back-illuminated sCMOS camera with a high-resolution 2X telecentric lens.
#16 - National Facility for Translational Medicine, Shanghai, China
The first mesoSPIM in China was set up in the group of Prof. Chunhai Fan as a apart of Biological Perspective project. The mesoSPIM was set up in October 2022 and its application is focused on brain imaging and studying intact human tissue. The imaging samples are mouse brains and other model organisms. Contact: Dr. Zhaoshuai Gao.
#17 - Eli and Edythe L. Broad Institute of MIT and Harvard, Cambridge, USA
The Broad mesoSPIM is part of the Optical Profiling Platform led by Sami Farhi. It saw first light in September 2022.
#18 - Lai Lab, Li Ka Shing Institute of Health Sciences, CUHK, Hong Kong
The first MesoSPIM in Hong Kong became operational in November 2022 and was set up by Jacky Hung.