The mesoSPIM (mesoscale selective plane illumination microscopy) project creates open-hardware microscopy platforms for imaging cleared tissue.
mesoSPIM features
Compatible with all clearing methods, simple and quick sample mounting and exchange, reduced shadowing artifacts and many moreā¦
Isotropy across large FOVs
The mesoSPIM is an axially scanned light-sheet microscope (ASLM) for uniform z-resolution across the FOV.
Image large Samples
Fits a whole mouse CNS with 52 x 52 x 102 mm travel range - a larger sample volume than any other available light-sheet microscope.
Meetings and Workshops
Members of the mesoSPIM initiative organize a variety of workshops for the community.
Find a mesoSPIM near you.
Currently, there are more than 20 mesoSPIM setups in operation around the world.